rsomics-coverage-core vs bam_tide vs rust-htslib

Genome-binned BAM read-coverage primitive (deeptools countReadsPerBin port): per-bin read counts over a BGZF BAM via rsomics-bamio, shared by rsomics-bam-signal (bamCoverage) and rsomics-bam-compare (bamCompare).

A fast and memory-efficient BAM processing toolkit for coverage calculation and quantification, designed as a scalable alternative to deeptools bamCoverage for large sequencing datasets. And additional BAM tools.

This library provides HTSlib bindings and a high level Rust API for reading and writing BAM files.